Classifier alone when the noun is clear: cái này, con kia
this one, that one
Pattern: [classifier] + này / đó / kia / nào · [number] + [classifier]
When it's clear what you mean, keep the classifier and drop the noun: cái này (this one), cái đó (that one, the one we're talking about), cái kia (that one over there), con này (this one, an animal), cuốn nào? (which one, a book). The classifier, the small counting word, stands in for the noun, much as "one" does in English.
This is how you point and buy: Cho em cái này. I'll have this one. Chị lấy cái nào? Which one would you like? Use the classifier the noun would take: trái này for fruit (in Hà Nội quả này), con kia for a fish or a puppy.
Này, đó, kia and nào can't stand on their own as "this one", "that one" or "which one". The classifier has to stay: muốn cái này, never muốn này. Đây doesn't work here either; it's for introducing (Đây là …), not for "this one".
Numbers work the same way. Once you know what's being counted, the number and the classifier are enough: Cho anh hai cái. Two, please. Em lấy ba trái. I'll take three.
When the thing isn't clear yet, say the noun: cái áo này (this shirt).
Examples
Highlighted words are what Saigon and Hà Nội say differently.
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Cho em cái này.
I'll have this one.
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Chị lấy cái nào?
Which one would you like?
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Saigon
Trái này ngọt không chị?
Hà Nội
Quả này ngọt không chị?
Is this one sweet?
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Con kia dễ thương quá!
That one's so cute!
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Saigon
Anh lấy hai cái nha.
Hà Nội
Anh lấy hai cái nhé.
I'll take two.